Exactly what is the active ingredient in Marquis? The Lively ingredient in MARQUIS, ponazuril, crosses the blood Mind barrier and targets the merozoite levels on the protozoa with out impacting mammalian cells rendering it a safe option for horses. MARQUIS paste kills Sarcocystis neurona to stop further more damage to the central anxious procedure.

The definitive host of EPM will be the opossum, which sheds infective sporocysts of S. neurona that infect horses.

The chosen dose of paste need to be deposited onto the again and leading of your horse's tongue. Introduce suggestion of paste syringe into your aspect of your horse's mouth at the Room among the entrance (incisor) and back again (molar) tooth.

 and stops the parasite from inflicting even more harm to the central nervous procedure. Concentrations achieved inside the CSF at regular condition were proven to kill ninety four% of 

Observe: The paste syringe is a multi-dose package deal. Make certain that the right dose is administered with Just about every use.

In case you miss out on a dose, give it after you bear in mind. Even so, whether it is near to time for the subsequent dose, skip the dose you skipped, give it at the subsequent scheduled time, and return to your common dosing program. Never give your dog two doses at once or give additional doses.

The reproductive protection of ponazuril hasn't been set up in equines. Consequently, usually do not administer this product to breeding mares or stallions.

VetLabel.com provides the full animal well being subset from the FDA's repository. Veterinary info provided Here's not meant as an alternative for direct session with an experienced veterinary Qualified.

muscle tissue exactly where they type muscle cysts, referred to as Sarcocysts. Intermediate hosts for EPM contain the nine banded armadillo, the

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The prognosis for animals treated for EPM might be dependent upon the severity of illness as well as the here duration in the infection prior to therapy.

Marquis paste is indicated to the therapy of equine protozoal myeloencephalitis (EPM) a result of Sarcocystis neurons.

A pharmacokinetic research was carried out in 8 horses to gather serum and cerebrospinal fluid (CSF) amounts of ponazuril immediately after only one dose of 5 mg/kg human body body weight. The believed parameter values were being utilized to product time focus profiles for ponazuril in serum and CSF. The design effects ended up utilized to estimate the dimensions with the loading dose necessary to guidance the accomplishment of constant condition serum and CSF amounts right after the initial dose.

Deposit paste around the horse’s tongue by depressing the plunger of the syringe in terms of the dosage ring permits. Take away tip of syringe from horse’s mouth.